1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
A study published in the Journal of Sexual Medicine and Neurology found that men with erectile dysfunction who took Cialis (tadalafil) and did not use it had an increased risk of developing a stroke. The results were presented at the European Society of Cardiology Annual Meeting on 18-19 July 2023. The study was conducted by the University of Bristol at the beginning of the 20th century and was recently published in the Journal of the American College of Cardiology in January 2024.
The researchers analysed data from more than 4,000 men from the male sexual dysfunction group (n = 4,061) who were not taking any drugs. They included participants who had erectile dysfunction (ED) and who had at least a one-year history of ED treatment. They tested the effect of the drugs on blood pressure and blood flow to the penis using a high-powered, non-invasive, computer-assisted device known as the Penis Stimulator. The researchers found that the drugs did not significantly reduce the risk of a stroke or heart attack. They concluded that Cialis did not increase the risk of developing a stroke or heart attack after taking tadalafil, while it did increase the risk of a stroke or heart attack. They also said that the drugs did not significantly alter the risk of a blood clot in people who took the drugs. The researchers said they therefore concluded that the drugs do not appear to do any harm in treating erectile dysfunction.
The study is part of the.
The researchers explained that they used the Penis Stimulation in a medical setting, which was not available in the UK. The research group also tested the use of Cialis in people who had a high risk of cardiovascular disease. The study was conducted in France. The researchers were able to detect a small increased risk of stroke in those who took tadalafil and used the erectile dysfunction drug Cialis. This is because tadalafil is known to increase blood flow to the penis, while Cialis increases blood flow to the penis and is also known to cause erectile dysfunction.
The researchers also found that tadalafil did not significantly reduce the risk of a stroke or heart attack in men who were taking the drug. They also found that the drug did not reduce the risk of a blood clot in people who took the drug. The study was published in the Journal of Sexual Medicine and Neurology in January 2024.
Dr Sarah Smith, Medical Director of Sexual Medicine and Neurology at the University of Bristol, said that the results are important because men with ED are at a higher risk of a stroke or heart attack. “This is because erectile dysfunction is a chronic disease and a condition that is often accompanied by cardiovascular disease and atherosclerotic cardiovascular disease, and this is where Cialis can be very effective.”
She said that the study did show that men with ED who took tadalafil and did not use it had an increased risk of a stroke or heart attack. However, there are many factors that can increase the risk of these diseases, including diabetes and hypertension. “The risk of a stroke or heart attack is higher in the group taking tadalafil,” she said.
“The group who took tadalafil had a slightly increased risk of having a stroke or heart attack compared with the group who took the placebo. There were also some other factors that may have increased the risk of stroke or heart attack.”
Dr Sarah Smith said that the results are not necessarily in line with other research, because there is no clear proof that Cialis is associated with a higher risk of a stroke or heart attack. She said that the results also do not agree with a scientific literature review that Cialis is generally safe and well-tolerated in people with ED and can be used to treat erectile dysfunction.
In her report, published in the Journal of Sexual Medicine and Neurology, the researchers found that men who took Cialis did not have a statistically significant increase in the risk of a stroke or heart attack compared to men who did not take the drug.
Erection problems (impotence) are very common, particularly in men over 40.
Most men occasionally fail to get or keep an erection. This is usually due to stress, tiredness, anxiety or drinking too much alcohol, and it’s nothing to worry about.
If it happens more often, it may be caused by physical or emotional problems.
Physical causes Possible cause Treatment Narrowing of penis blood vessels, high blood pressure, high cholesterol medicine to lower blood pressure, statins to lower cholesterol Hormone problems hormone replacement – for example, testosterone Side effects of prescribed medication change to medicine following discussion with GP You may also be asked to make lifestyle changes.
Do lose weight if you’re overweight stop smoking eat a healthy diet exercise daily try to reduce stress and anxiety
Don’t cycle for a while (if you cycle more than 3 hours a week) drink more than 14 units of alcohol a week
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. These effects are normally mild to moderate in nature.
If you experience any of the following side effects stop using the medicine and seek medical help immediately:
allergic reactions including rashes (frequency uncommon). chest pain – do not use nitrates but seek immediate medical assistance (frequency uncommon). priapism, a prolonged and possibly painful erection after taking CIALIS (frequency rare). If you have such an erection, which lasts continuously for more than 4 hours you should contact a doctor immediately. sudden loss of vision (frequency rare). Other side effects have been reported:
Common (seen in 1 to 10 in every 100 patients)
headache, back pain, muscle aches, pain in arms and legs, facial flushing, nasal congestion, and indigestion. Uncommon (seen in 1 to 10 in every 1,000 patients)
dizziness, stomach ache, feeling sick, being sick (vomiting), reflux, blurred vision, eye pain, difficulty in breathing, presence of blood in urine, prolonged erection, pounding heartbeat sensation, a fast heart rate, high blood pressure, low blood pressure, nose bleeds, ringing in the ears, swelling of the hands, feet or ankles and feeling tired. Rare (seen in 1 to 10 in every 10,000 patients)
fainting, seizures and passing memory loss, swelling of the eyelids, red eyes, sudden decrease or loss of hearing, hives (itchy red welts on the surface of the skin), penile bleeding, presence of blood in semen and increased sweating. Heart attack and stroke have also been reported rarely in men taking CIALIS. Most of these men had known heart problems before taking this medicine.
Partial, temporary, or permanent decrease or loss of vision in one or both eyes has been rarely reported.
Stop taking CIALIS and seek immediate medical assistance (frequency rare)
Treatable or self-lim down (greater than or equal to or greater than 70mg daily) repeat tablet take only if prescribed. Dosage and duration of treatmententleness and sedation will usually start toocused on the treatment. When this is not an possibility, attempts can be made to limit intake. taking CIALIS tablets (CIALIS 20mg, 40mg, 80mg, and 100mg)
Possible effects of CIALIS tablets in the pregnancy
The medicine is not recommended for use in children below 18 years if you are pregnant.
This medicine is not recommended during pregnancy.
This medicine is not recommended in men who are pregnant.
The pregnant woman should not take this medicine.
Levitra usage has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious effects, seek medical attention immediately.
Common side effects reported from Levitra use include:
More serious side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a serious adverse reaction to this medication and immediately require treatment.
As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Levitra. Levitra can interact with bodily substances, causing potentially serious adverse reactions.
Do not take Levitra if you take nitrate medications such as isosorbide dinitrate, isosorbide mononitrate, and nitroglycerin. It’s important to inform your doctor if you are taking any form of high blood pressure medication, alpha-blocker medication, prescription antifungals (like fluconazole), or other medications for erectile dysfunction. You should include information about herbal products, especially St. John’s wort.
Do not drink grapefruit juice while taking Levitra.
Talk to your health care provider about safe drinking practices during treatment with Levitra. Levitra can interact with alcohol and cause potentially serious adverse reactions like those above.
Xinwen Liu is a freelance writer and editor who writes extensively about health and lifestyle issues. She is a member of Theros Lawrens List and Theros Lawrens List Publishing Trust.adiator: Healthline is a news website. We are unable to publish content that is not directly endorsed by The Los Angeles County Manohamen and Cinum Medical Center.
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